Figure 5.

Sch B-induced apoptosis via regulation of Caspase and Bcl-2 family members in gallbladder cancer cells. (A) GBC-SD and NOZ cells were treated with Sch B (0, 30, 60, and 90 μmol/L) for 48 h. The expression levels of Bcl-2, Bax, cleaved caspase-9, cleaved caspase-3, cleaved PARP and NF-κB were detected by western blot analysis, and GAPDH was used as a loading control; (B) The data of the relative ratio of Bcl-2 to Bax (mean ± SD); The results shown were representative data from 3 independent experiments. * P < 0.05, ** P < 0.01 vs. the control group.