Table 1.
Assessment of the mutagenicity of 7,8,3'-trihydroxy-4'-methoxyisoflavone (TM) against S. typhimurium. The table shows the revertants per plate, the standard deviation and the mutagenicity index (in brackets) for strains TA98 and TA97a after treatment with TM.
| TM | ||||
|---|---|---|---|---|
| Treatment | TA 98 | TA 97a | ||
| mg/plate | −S9 | +S9 | −S9 | +S9 |
| DMSO | 20 ± 2 | 30 ± 2 | 151 ± 8 | 143 ± 8 |
| 0.19 | 20 ± 4 (1.0) | 34 ± 3 (1.1) | 194 ± 4 (1.3) | 172 ± 4 (1.2) |
| Control+ | 1319 ± 41 a | 1696 ± 41 b | 1875 ± 62 a | 1623 ± 48 b |
The values are the mean ± SEM of two determinations. DMSO: dimethyl sulfoxide (50 μL/plate; negative control); Control+: positive control; a 4-nitro-o-phenylenediamine (10 μg/plate); b 2-anthramine (1.25 μg/plate).