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Syntheses of 1,2,3-triazoles-quinazoline 6a–i and 7a–i.
Reaction conditions: (i) 5a/4b–c (1 mmol), alkylazide (2.5 mmol), Et3N (1.1 mmol), CuI (0.1 eq), MWI (400W, 2 min); (ii) 6a,d,g (1 mmol), NaOMe (1 eq), MeOH, r.t (30 min) or 6b–c,e,f,h,i (1 mmol), K2CO3 (1 eq), MeOH, r.t (15 min).
