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Effects of cudraflavone B on glutamate-induced oxidative neurotoxicity (A) and ROS generation (B) in HT22 cells.HT22 cells were pre-treated with cudraflavone B for 12 h and then incubated for 12 h with glutamate (5 mM). Exposure of HT22 cells to glutamate increased ROS production. Data are presented as mean ± SD values of three independent experiments. Trolox (50 μM) was used as the positive control. * p < 0.05 vs. glutamate.
