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. 2014 Jul 24;19(8):10818–10831. doi: 10.3390/molecules190810818

Figure 6.

Figure 6

Effects of cudraflavone B-induced HO-1 expression through the PI3K/AKT cascade in HT22 cells. HT22 cells were treated with cudraflavone B (40 μM) for the indicated times (A); HT22 cells were pre-incubated with or without 10 μM LY294002 for 1 h and then incubated in the absence or presence of 40 μM of cudraflavone B for 12 h (B) or 30 min (C). HT22 cells untreated or treated with cudraflavone B (40 μM) in the presence or absence of LY294002 (10 μM) for 12 h were exposed to 5 mM glutamate for 12 h (D, E). Data are presented as the mean ± SD values of three independent experiments. * p < 0.05.