Table 1.
DPPH scavenging activity and iron chelating activity of thiadiazine derivatives a.
| Compound | % DPPH scavenging activity | % Chelating activity |
|---|---|---|
| ascorbic acid b | 85.2 ± 6.1 | - |
| EDTA c | - | 90.9 ± 7.22 |
| 4a | 17.2 ± 0.59 | 0.0 |
| 4b | 90.0 ± 1.24 | 15.1 ± 4.27 |
| 5a | 36.0 ± 2.07 | - |
| 5b | 94.4 ± 1.73 | 0 |
| 5c | 17.7 ± 1.26 | 0,0 |
| 5d | 33.3 ± 0.27 | - |
| 5e | 80.7 ± 1.61 | 0.0 |
| 5f | 94.1 ± 1.35 | 0.0 |
| 5g | 82.3 ± 0.70 | 0.0 |
| 5h | 80.6 ± 0.98 | 62.5 ± 2.25 |
| 5i | 79.7 ± 1.29 | 5.3 ± 0.56 |
| 5j | 90.0 ± 1.08 | 53.5 |
| 5k | 77.2 ± 0.93 | 5.18 ± 0.81 |
| 5l | 80.2 ± 0.44 | 10.2 ± 0.42 |
a data are means ± standard deviation of three replicates; b ascorbic acid was used as standard in DPPH scavenging activity determination; c EDTA was used as standard in iron chelating activity determination.