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. 2014 Nov 26;19(12):19610–19632. doi: 10.3390/molecules191219610

Table 1.

Flavonoids identified in propolis since 2000.

No. Chemical Name Geographical Location Reference
Flavones
1 Luteolin China [33]
2 6-Cinnamylchrysin China [34]
3 3',5-Dihydroxy-4',7-dimenthoxy flavone Poland [26]
4 Hexamethoxy flavone Egypt [35]
5 (7''R)-8-[1-(4'-Hydroxy-3'-methoxyphenyl) prop-2-en-1-yl]chrysin Mexico [36]
Flavonols
6 2'-(8"-Hydroxy-3",8"-dimethyl-oct-2"-enyl)-quercetin Solomon Island [31]
7 8-(8"-Hydroxy-3",8"-dimethyl-oct-2"-enyl)-quercetin Solomon Island [31]
8 2'-Geranylquercetin Solomon Island [31]
9 Macarangin Kenya [37]
10 (7"R)-8-[1-(4'-Hydroxy-3'-methoxyphenyl)prop-2-en-1-yl]-galangin Mexico [36]
Flavanones
11 3-O-[(S)-2-Methylbutyroyl]pinobanksin China [34]
12 (2S)-5,7-Dihydroxy-4'-methoxy-8-prenylflavanone Solomon Island [31]
13 Hesperitin-5,7-dimethyl ether Portugal [38]
14 Pinobanksin-5-methyl-ether-3-O-pentanoate Portugal [38]
15 7-O-Prenylstrobopinin Greek [39]
16 7-O-Prenylpinocembrin Greek [39]
17 (2R,3R)-3,5-Dihydroxy-7-methoxyflavanone 3-(2-methyl)-butyrate Mexico [36]
18 (2R,3R)-6[1-(4'-Hydroxy-3'-methoxyphenyl) prop-2en-1-yl] pinobanksin Mexico [40]
19 (2R,3R)-6[1-(4'-Hydroxy-3'-methoxyphenyl) prop-2en-1-yl]-pinobanksin-3-acetate Mexico [40]
20 3',4',6-Trihydroxy-7-methoxy flavanone Nepal [41]
21 5,7,3',4'-Tetrahydroxy-5'-C-geranylflavanone Japan [42]
22 5,7,3',4'-Tetrahydroxy-6-C-geranylflavanone Japan [42]
23 5,7,3',4'-Tetrahydroxy-2'-C-geranylflavanone Japan [42]
24 5,7,3',4'-Tetrahydroxy-2'-C-geranyl-6-prenlyflavanone Japan [42]
25 Propolin A Taiwan [43]
26 Propolin B Taiwan [43]
27 Propolin E Taiwan [43]
28 Sigmoidin B Taiwan [43]
29 Bonannione A Taiwan [31]
30 Solophenol A Solomon Island [31]
31 Sophoraflavanone A Solomon Island [31]
32 (2S)-7-Hydroxyflavanone Brazil [44]
33 (2S)-Liquiritigenin Brazil [44]
34 (2S)-7-Hydroxy-6-methoxyflavanone Brazil [44]
35 (2S)-Naringenin Brazil [44]
36 (2S)-Dihydrobaicalein Brazil [44]
37 (2S)-Dihydrooroxylin A Brazil [44]
38 (2R,3R)-3,7-Dihydroxyflavanone Brazil [44]
39 Garbanzol Brazil [44]
40 (2R,3R)-3,7-Dihydroxy-6-methoxyflavanone Brazil [44]
41 Alnustinol Brazil [44]
42 (2R, 3R)-3,6,7-Trihydroxyflavanone Nepal [41]
43 5-Methoxy-3-hidroxyflavanone Portugal [38]
44 5,7-Dihydroxy-6-methoxy-2,3-Dihydroflavonol-3-acetate Australia [45]
Isoflavones
45 Odoratin Nepal [41]
46 7,3',4'-Trihydroxy-5'-methoxyisoflavonoid Nepal [41]
47 6,7,3'-Trihydroxy-4'-methoxyisoflavonoid Nepal [41]
48 7,3'-Dihydroxy-6,5'- methoxyisoflavonoid Nepal [41]
49 7-Hydroxy-4'-methoxyisoflavonoid Cuba [46]
50 5,7-Dihydroxy-4'-methoxyisoflavonoid Cuba [46]
51 Calycosin Brazil [44]
52 7,4'-Dihydroxyisoflavone Brazil [24]
53 Homopterocarpin Brazil [24]
54 Medicarpin Brazil [24]
55 4',7-Dimethoxy-2'-isoflavonol Brazil [24]
Isodihydroflavones
56 Daidzein Brazil [44]
57 Formononetin Brazil [44]
58 Xenognosin B Brazil [44]
59 Biochanin A Brazil [44]
60 Pratensein Brazil [44]
61 2'-Hydroxybiochanin A Brazil [44]
62 (3S)-Vestitone- Brazil [44]
63 (3S)-Violanone Brazil [44]
64 (3S)-Ferreirin Brazil [44]
65 (3R)-4'-Methoxy-2',3,7-trihydroxyisoflavanone Brazil [44]
66 Biochanin Cuba [25]
Chalcones
67 3,4,2',3'-Tetrahydroxychalcone Brazil [30]
68 Isoliquiritigenin Brazil [44]
69 4,4'-Dihydroxy-2'-methoxychalcone Brazil [44]
Dihydrochalcones
70 S)-α,2',4,4'-Tetrahydroxydihydrochalcone Brazil [44]
71 2',4'-Dihydroxychalcone Brazil [44]
72 2',6'-Dihydroxy-4',4-dimethoxydihydrochalcone Canada [47]
73 2',4',6'-Trihydroxy-4-methoxydihydrochalcone Canada [47]
74 2',6',4-Tryhydroxy-4'-methoxydihydrochalcone Canada [47]
Flavans
75 8-[(E)-4-Phenylprop-2-en-1-one]-(2R,3S)-2-(3,5-dihydroxyphenyl)-3,4-dihydro-2H-2-be-nzopyran-5-methoxyl-3,7-diol, China [48]
76 8-[(E)-4-Phenylprop-2-en-1-one]-(2S,3R)-2-(3,5-dihydroxyphenyl)-3,4-dihydro-2H-2-benzopyran-5-methoxyl-3,7-diol China [48]
77 8-[(E)-4-Phenylprop-2-en-1-one]-(2R,3S)-2-(3-methoxyl-4-hydroxyphenyl)-3,4-dihydro-2H-2-benzopyran-5-methoxyl-3,7-diol China [48]
78 3-Hydroxy-5,6-dimethoxyflavan Mexico [49]
Isoflavans
79 (3S)-Vestitol Brazil [44]
80 (3S)-Isovestitol Brazil [44]
81 (3S)-7-O-Methylvestitol Brazil [44]
82 (3S)-Mucronulatol Brazil [44]
83 7,4'-Dihydroxy-2'-methoxyisoflavone Cuba [46]
84 Neovestitol Cuba [25]
Pterocarpins (a type of neoflavonoid)
85 Medicarpin Cuba [46]
86 4-Hydroxymedicarpin - [46]
87 Homopterocarpin Cuba [46]
88 4'-Methoxy-5'hydroxyvesticarpan - [46]
89 3,8-Dihydroxy-9-methoxypterocarpan Cuba [46]
90 3-Hydroxy-8,9-dimethoxypterocarpan Cuba [46]
91 3,4-Dihydroxy-9-methoxypterocarpan Cuba [46]
92 3,10-Dihydroxy-9-methoxypterocarpan Brazil [44]
93 6a-Ethoxymedicarpin Brazil [44]
94 (6aR,11aR)-4-Methoxymedicarpin Brazil [44]
Open-chain neoflavonoids
95 Neoflavonoid 1 Nepal [50]
96 Neoflavonoid 2 Nepal [50]
97 Neoflavonoid 3 Nepal [50]
98 Neoflavonoid 4 Nepal [50]
99 Neoflavonoid 5 Nepal [50]
100 Neoflavonoid 6 Nepal [50]
101 Neoflavonoid 7 Nepal [50]
102 Neoflavonoid 8 Nepal [50]
103 Neoflavonoid 9 Nepal [50]
104 Neoflavonoid 10 Nepal [50]
105 (S)-3'-hydroxy-4-methoxydalbergione Nepal [51]
106 (S)-3',4'-dihydroxy-4-methoxydalbergione Nepal [51]
107 (S)-4-methoxydalbergione Nepal [51]
Other flavonoids
108 2,6-Dihydroxy-2-[(4-hydroxyphenyl)methyl]-3-benzofuranone Brazil [44]
109 2-(2',4'-Dihydroxyphenyl)-3-methyl-6-methoxybenzofuran Brazil [44]
110 1-(3',4'-Dihydroxy-2'-methoxyphenyl)-3-(phenyl)propane Mexico [49]
111 (Z)-1-(2'-Methoxy-4',5'dihydroxyphenyl)-2-(3-phenyl)propene Mexico [49]