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The synthesis route of compounds 5–29.
Reagents and conditions: (i) BH3.S(CH3)2, THF, 0 °C for 1 h, and room temperature for 10 h; (ii) sesamol, K2CO3, CH3CN, reflux, 16 h; (iii) TsCl, Et3N and 4-dimethylaminopyridine, Cl2CH2, 0 °C, 16 h; (iv) arylpiperazines, K2CO3, CH3CN, reflux, 16 h; (v) phenylpiperidines, K2CO3, CH3CN, reflux, 16 h.
