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. 2014 Dec 22;19(12):21560–21578. doi: 10.3390/molecules191221560

Figure 2.

Figure 2

Figure 2

Representative MRM chromatograms of gentiopicroside (channel 1), geniposide (channel 2), baicalin (channel 3), swertiamarin (channel 4), and carvedilol (IS) (channel 5) in rat plasma: (A) blank plasma samples; (B) blank plasma samples spiked with gentiopicroside, geniposide, baicalin, swertiamarin, and carvedilol (IS) at 500, 50, 100, 25, and 10 ng/mL, respectively; (C) diluted plasma sample (×10) of gentiopicroside, geniposide, and baicalin at 240 min, and plasma sample of swertiamarin at 90 min, after oral administration of Long-Dan-Xie-Gan-Tang (10 g/kg, p.o.).