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(A) Antiproliferative action of doxorubicin against parental (□) and MDR (■) mouse lymphoma cells; (B) Antiproliferative actions of 3 (□), 4 (■) and 5 (♦) against MDR mouse lymphoma cells; and (C) Antiproliferative effects of the solanidine analogs (1–9 and 11–18, 5 µM) combined with 0.1 µM doxorubicin.
