Skip to main content
. 2014 Feb 17;19(2):2061–2076. doi: 10.3390/molecules19022061

Table 1.

QRT-PCR analysis of cell cycle related genes in response to drug treatment.

10
6-h incubation 12-h incubation 24-h incubation
GeneName RefSeqID 10 M 20 M 30 M 10 M 20 M 30 M 10 M 20 M 30 M
TNFα; tumor necrosis factor alpha NM_000594 −1.02 −1.08 −1.23 1.51 −3.90 −8.41 1.72 −1.87 −4.00
GADD45alpha NM_001924 1.59 1.04 1.24 1.16 1.28 1.72 1.14 5.19 3.65
TXNRD1; thioredoxin reductase 1 NM_003330 1.24 −1.73 −1.11 −1.40 −1.39 −1.42 1.78 1.90 1.28
SKP2; S-phase kinase-assoc. prot. 2 NM_005983 1.87 −1.55 −1.43 −1.06 −1.53 2.11 −4.58 −7.60 −8.04
APC4; anaphase-promoting complex 4 NM_013367 1.31 1.25 1.22 1.27 1.45 1.03 −2.45 −2.16 −2.23
CCND1; cyclin D1 NM_053056 −1.42 1.05 −1.04 1.25 1.57 −1.30 −1.43 −2.14 −4.36
CCNE2; cyclin E2 NM_057749 1.04 −1.12 1.09 1.24 1.23 −1.08 1.23 1.13 −1.23
CDKN2B; cyclin-dependent kinase inhib. 2B NM_078487 −1.22 −1.26 1.27 1.05 −1.50 1.02 −2.74 −7.11 −9.36
16
6-h incubation 12-h incubation 24-h incubation
GeneName RefSeqID 10 M 20 M 30 M 10 M 20 M 30 M 10 M 20 M 30 M
TNFα; tumor necrosis factor alpha NM_000594 1.56 -1.76 −1.69 −1.13 −1.72 −1.75 −2.23 1.16 1.45
GADD45alpha NM_001924 −1.02 1.12 1.27 1.67 1.38 −1.07 1.78 1.86 2.63
TXNRD1; thioredoxin reductase 1 NM_003330 1.01 1.14 1.01 1.68 −1.18 1.37 2.42 2.01 2.60
SKP2; S-phase kinase-assoc. prot. 2 NM_005983 1.03 −1.08 1.67 1.74 1.34 2.10 −1.40 −1.87 −1.30
APC4; anaphase-promoting complex 4 NM_013367 −1.10 1.26 1.43 1.75 1.08 1.11 −1.28 −1.90 −1.43
CCND1; cyclin D1 NM_053056 1.15 1.11 1.63 1.07 1.22 1.09 −1.60 −1.01 −1.19
CCNE2; cyclin E2 NM_057749 1.09 1.30 1.48 1.94 1.44 1.83 −1.33 −2.62 −2.33
CDKN2B; cyclin-dependent kinase inhib. 2B NM_078487 1.69 1.18 2.27 -1.61 1.96 1.88 −6.22 −7.86 −14.83