Table 3.

MW _vs. US method in the intramolecular Friedel-Craft acylation of phenyl propionic acids 1–7.

Entry	Product	US-Assisted Reaction a			MW-Assisted Reaction a			Q-Tube-Assisted Reaction a
		Time (min)	Conv (%)	Yield (%)	Time (min)	Conv (%)	Yield(%)	Time (min)	Conv (%)	Yield(%)
1		150	100	100	60	100	100	60	100	100
		210 b	100	100	90 b	100	100	90 b	100	100
2		60	100	88/12	60	100	90/10	60	100	90/10
				(2b)/(2a)			(2b)/(2a)			(2b)/(2a)
3		120	100	- c	180	100	- c	180	100	- c
4		60	100	100	60	100	100	60	100	100
5		60	100	100	60	100	100	60	100	100
6		360	-	-	180	-	-	180	-	-
7		360	100	100	180 d	42	33	180 d	54	36
					60 e	100	100	60 e	100	100
8		1200	90	90	180 d	58	48	180 d	44	43
					60 e	100	100	60 e	100	100
9		60	100	100	180	100	100	180	100	100
10		60	100	100	60	100	100	60	100	100
11		60	100	85/15	60	100	88/12	60	100	88/12
				(11b)/(11a)			(11b)/(11a)			(11b)/(11a)
12		400	100	100	180 d	38	30	180 d	45	33
					60 e	100	100	60 e	100	100
13		460	100	100	180 d	32	28	180 d	40	36
					120 e	100	100	120 e	100	100
14		1200 d	-	-	360 e	-	-	360 e	-	-

^a All new products were characterized by GC/MS and ¹H-NMR spectroscopy; all the known products were characterized by comparison with the spectral data in the literature; ^b Reaction conducted with 5.0 mmol of reactant; ^c Formation of poli-ketones by polymerization; ^d Reaction conducted in presence of 5 eq. of TfOH; ^e Reaction conducted in presence of 10 equivalents of TfOH.