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. 2014 Mar 24;19(3):3761–3776. doi: 10.3390/molecules19033761

Scheme 1.

Synthesis of CPT-bile acid analogues.

Scheme 1

Reagents: (a) EDCI, DMAP, and CH2Cl2; (b) HCl/MeOH; (c) TEA and DMSO; (d) TEA and DMF; (e) K2CO3 and DMF. (CA = cholic acid; DCA = deoxycholic acid; UDCA = ursodeoxycholic acid; CDCA = chenodeoxycholic acid).