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(A) Type-I procollagen synthesis and (B) MMP-1 inhibition of fibroblast CCD-986sk cells after CopA3 treatment. Fibroblast cells were exposed to UVB for 1 min and treated with various concentrations of CopA3. Type-I procollagen synthesis and MMP-1 inhibition were measured with an assay kit. All experiments were performed in triplicate. Values shown are means ± SEM (n = 3). * p < 0.05; ** p < 0.01 versus the control group. EGCG was used at 25 µg/mL.
