Table 1.
Variable | Reference range | Treatment | Time after VR, hours | ||||
---|---|---|---|---|---|---|---|
BL | 0.5 | 2 | 4 | 24 | |||
Hematocrit, % | 38‐48 | Control | 43 ± 3 | 41 ± 4a | 40 ± 2a | 40 ± 2a | 45 ± 3a |
LRS | 41 ± 2 | 32 ± 2b | 34 ± 2b | 37 ± 3b | 36 ± 3b | ||
TS | 42 ± 3 | 32 ± 4b | 35 ± 2b | 36 ± 1b | 39 ± 3c | ||
Platelet count, ×103/μL | 200‐500 | Control | 332 ± 44 | 346 ± 67a | 327 ± 36a | 317 ± 48a | 314 ± 43a |
LRS | 323 ± 57 | 213 ± 47b | 262 ± 61b | 252 ± 67b | 242 ± 35b | ||
TS | 302 ± 42 | 232 ± 28b | 291 ± 54ab | 294 ± 40ab | 268 ± 16b | ||
BMBT, second | <240 | Control | 61 ± 16ab | 63 ± 15 | 57 ± 14 | 56 ± 12 | 97 ± 40 |
LRS | 86 ± 22a | 56 ± 14 | 60 ± 19 | 52 ± 15 | 80 ± 38 | ||
TS | 50 ± 16b | 74 ± 21 | 79 ± 35 | 51 ± 21 | 76 ± 39 | ||
PT, second | 11‐17 | Control | 15 ± 1 | 15 ± 1a | 17 ± 3 | 15 ± 2 | 13 ± 1 |
LRS | 14 ± 1 | 16 ± 2a | 15 ± 1 | 15 ± 1 | 13 ± 1 | ||
TS | 14 ± 1 | 13 ± 1b | 16 ± 1 | 14 ± 1 | 13 ± 1 | ||
aPTT, second | 72‐102 | Control | 72 ± 9 | 73 ± 9 | 75 ± 14 | 73 ± 9a | 80 ± 11 |
LRS | 75 ± 12 | 92 ± 29 | 82 ± 15 | 83 ± 9ab | 87 ± 6 | ||
TS | 79 ± 15 | 89 ± 24 | 90 ± 14 | 91 ± 16b | 79 ± 10 |
Within each column. For a given time point, treatment group means followed by different superscript letters are significantly different from each other (Tukey's test, P ≤ 0.05).