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. 2018 Oct 25;32(6):1927–1933. doi: 10.1111/jvim.15327

Table 1.

Hematocrit, platelet count, buccal mucosal bleeding time (BMBT), prothrombin time (PT), activated partial thromboplastin time (aPTT). Data represent the mean ± SD of 6 dogs that did not undergo acute hemorrhage followed by volume replacement (VR) in one occasion (control treatment) or that underwent hemorrhage and randomly received VR with lactated Ringer's solution (LRS treatment) or with 6% tetrastarch solution (TS treatment) at a ratio of 3:1 or 1:1 the volume of shed blood, respectively. Variables were recorded during anesthesia, before hemorrhage (BL), 0.5, 2, and 4 hours after VR. Anesthesia was interrupted 4 hours after VR, and data were collected 24 hours after VR

Variable Reference range Treatment Time after VR, hours
BL 0.5 2 4 24
Hematocrit, % 38‐48 Control 43 ± 3 41 ± 4a 40 ± 2a 40 ± 2a 45 ± 3a
LRS 41 ± 2 32 ± 2b 34 ± 2b 37 ± 3b 36 ± 3b
TS 42 ± 3 32 ± 4b 35 ± 2b 36 ± 1b 39 ± 3c
Platelet count, ×103/μL 200‐500 Control 332 ± 44 346 ± 67a 327 ± 36a 317 ± 48a 314 ± 43a
LRS 323 ± 57 213 ± 47b 262 ± 61b 252 ± 67b 242 ± 35b
TS 302 ± 42 232 ± 28b 291 ± 54ab 294 ± 40ab 268 ± 16b
BMBT, second <240 Control 61 ± 16ab 63 ± 15 57 ± 14 56 ± 12 97 ± 40
LRS 86 ± 22a 56 ± 14 60 ± 19 52 ± 15 80 ± 38
TS 50 ± 16b 74 ± 21 79 ± 35 51 ± 21 76 ± 39
PT, second 11‐17 Control 15 ± 1 15 ± 1a 17 ± 3 15 ± 2 13 ± 1
LRS 14 ± 1 16 ± 2a 15 ± 1 15 ± 1 13 ± 1
TS 14 ± 1 13 ± 1b 16 ± 1 14 ± 1 13 ± 1
aPTT, second 72‐102 Control 72 ± 9 73 ± 9 75 ± 14 73 ± 9a 80 ± 11
LRS 75 ± 12 92 ± 29 82 ± 15 83 ± 9ab 87 ± 6
TS 79 ± 15 89 ± 24 90 ± 14 91 ± 16b 79 ± 10

Within each column. For a given time point, treatment group means followed by different superscript letters are significantly different from each other (Tukey's test, P ≤ 0.05).