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. 2018 Oct 26;109(12):3695–3706. doi: 10.1111/cas.13812

Figure 4.

Figure 4

Methylation value increased as the tumor progressed. A, In colorectal carcinogenesis, the CDO1 methylation level increased significantly during the course of Vogelstein adenoma carcinoma sequence (P < .0001). B, In gallbladder carcinogenesis, the CDO1 methylation level increased significantly as the disease progressed from stage I to stage II