Table 1.
Protein | Type | Producing Fungus | Target Organism | Target Polysaccharide/Glycoconjugate | Target Glycoepitope (in vitro/in vivo) | References | |
---|---|---|---|---|---|---|---|
AFP | Non-classical defensin-like | Aspergillus giganteus | Filamentous fungi | Chitin Glucosylceramide |
(GlcNAc-β1,4)n-GlcNAc Glc |
[23] | |
PAF | Non-classical defensin-like | Penicillium chrysogenum | Filamentous fungi | Chitin? Glucosylceramide? |
(GlcNAc-β1,4)n-GlcNAc? Glc? |
[24] | |
BP | Non-classical defensin-like | Penicillium brevicompactum | Filamentous fungi | Chitin? Glucosylceramide? |
(GlcNAc-β1,4)n-GlcNAc? Glc? |
[25] | |
LysM-effector | Various | Filamentous fungi Gram-positive bacteria? |
Chitin Peptidoglycan? |
(GlcNAc-β1,4)n-GlcNAc (MurNAc-β1,4-GlcNAc)n? |
[33] | ||
Thaumatin-like | Various | Filamentous fungi | β1,3-glucans | (Glc-β1,3)n-Glc | [39] | ||
AAL | Hololectin | Aleuria aurantia | Zygomycetes Insects Nematodes Amoeba |
Fucose-containing polysaccharides Fucose-containing N- and/or O-glycans? |
Fuc-α1,x-X | [44,47,48,49] | |
Plectasin | Csαβ defensin-like | Pseudoplectania nigrella | Gram-positive bacteria | Lipid II | ? | [6] | |
Eurocin | Csαβ defensin-like | Eurotium amstelodami | Gram-positive bacteria | Lipid II | ? | [50] | |
Micasin | Csαβ defensin-like | Microsporum canis | Gram-positive and -negative bacteria | Lipid II | ? | [51] | |
Copsin | Csαβ defensin-like | Coprinopsis cinerea | Gram-positive bacteria | Lipid II | ? | [52] | |
GH24-lysozyme | Various | Gram-positive bacteria | Peptidoglycan | (MurNAc-β1,4-GlcNAc)n | |||
GH25-lysozyme | Chalaropsis sp. | Gram-positive bacteria | Peptidoglycan | (MurNAc-β1,4-GlcNAc)n | [53] | ||
Ceratoplatanin | Various | Filamentous fungi? Gram-positive bacteria? |
Chitin? Peptidoglycan? |
(GlcNAc-β1,4)n-GlcNAc? (MurNAc-β1,4-GlcNAc)n? |
[54,55] | ||
XCL | Hololectin | Xerocomus chrysenteron | Insects Nematodes |
N- and/or O-glycans | Gal-β1,3-GalNAc and GlcNAc-β1,2-Man | [47,56,57] | |
TAP1 | Hololectin | Sordaria macrospora | Insects Nematodes Amoeba |
O-glycans? | Gal-β1,3-GalNAc | [47,57] | |
CCL2 | Hololectin | Coprinopsis cinerea | Insects Nematodes |
N-glycan core | GlcNAc-β1,4(Fuc-α1,3)-GlcNAc | [19,57] | |
CNL | Hololectin | Clitocybe nebularis | Mammalian cells Nematodes Amoeba |
O-glycans? | GalNAc | [47,58] | |
MPL | Hololectin | Macrolepiota procera | Nematodes | N- and/or O-glycans? | Gal-β1,4-GlcNAc | [59] | |
SSA | Hololectin | Sclerotinia sclerotiorum | Insects Amoeba |
N- and/or O-glycans? | GalNAc/Gal | [47,60] | |
RSA | Hololectin | Rhizoctonia solani | Insects | N- and/or O-glycans? | GalNAc/Gal | [61,62,63] | |
CGL1/2 | Hololectin | Coprinopsis cinerea | Insects Nematodes Amoeba |
N- and/or O-glycans? N-glycan core N- and/or O-glycans? |
Gal-β1,4-Glc Gal-β1,4-GlcNAc Gal-β1,4-Fuc |
[47,57] | |
Tectonin2 | Hololectin | Laccaria bicolor | Nematodes | N-glycan antenna | 2-O-Me-Fuc/3-O-Me-Man | [20] | |
MOA | Chimerolectin | Marasmius oreades | Nematodes | Glycosphingolipids | Gal-α1,3-GalNAc | [64,65,66] | |
LSL | Chimerolectin | Laetiporus sulphureus | Mammalian cells | ? |
Gal-β1,4-Glc Gal-β1,4-GlcNAc |
[67,68] |