Table 1.

The anti-inflammatory activity of the tested compounds and reference drug (Indomethacin) in carrageenan-induced rat paw edema assay, Values are expressed as mean ± SEM, (n = 8).

Groups	Increase in Paw Volume (Edema Volume) (mL)
	0 h	1 h	2 h	3 h
Control	0.42 ± 0.01	0.71 ± 0.01	0.8 ± 0.01	0.84 ± 0.01
Indomethacin (10 mg/kg)	0.45 ± 0.01	0.65 ± 0.02	0.60 ± 0.02 ***	0.56 ± 0.02 ***
1	0.44 ± 0.03	0.66 ± 0.03	0.72 ± 0.03	0.64 ± 0.03 ***
2	0.43 ± 0.02	0.58 ± 0.02 **	0.68 ± 0.02 **	0.61 ± 0.02 ***
3	0.46 ± 0.02	0.56 ± 0.02 ***	0.66 ± 0.02 ***	0.57 ± 0.02 ***
4	0.40 ± 0.02	0.50 ± 0.02 ***	0.57 ± 0.02 ***	0.47 ± 0.02 ***
5	0.46 ± 0.03	0.63 ± 0.03	0.70 ± 0.03 **	0.60 ± 0.03 ***
6	0.41 ± 0.02	0.64 ± 0.02	0.68 ± 0.02 **	0.58 ± 0.02 ***
7	0.43 ± 0.03	0.68 ± 0.03	0.72 ± 0.03	0.60 ± 0.03 ***
8	0.47 ± 0.01	0.65 ± 0.01	0.58 ± 0.01 ***	0.52 ± 0.01 ***
9	0.43 ± 0.01	0.59 ± 0.01 **	0.63 ± 0.01 ***	0.66 ± 0.02 ***
10	0.48 ± 0.03	0.61 ± 0.03	0.76 ± 0.03	0.64 ± 0.03 ***
11	0.42 ± 0.01	0.66 ± 0.01	0.63 ± 0.01 ***	0.57 ± 0.01 ***

** Significant difference at p < 0.01 and *** Significant difference at p < 0.001.