Table 3.

Interaction energies of compounds 1–11 with the COX-1 and COX-2 enzymes.

Compound No.	Chemical Structure	dG (COX-1) Kcal/mole	dG(COX-2) Kcal/mole
Reference		−11.5716	−11.1006
1		−12.2721	−10.5499
2		−11.5564	−10.7125
3		−11.1199	−10.9148
4		−13.5408	−11.2977
5		−11.3127	−11.1787
6		−11.5776	−10.7572
7		−11.0632	−10.9992
8		−12.4821	−12.2774
9		−11.3067	−10.4561
10		−11.7976	−11.2097
11		−11.3457	−10.8248