Table 1.
IC50 values of the isolated compounds in the AChEI assay 1.
| Compound | IC50 (µM) | Compound | IC50 (µM) |
|---|---|---|---|
| α-Glutinol (1) | inactive | Luteolin (9) | more than 500 (30% at 250 µM) 3 |
| β-Amyrin (2) | inactive | Methyl chlorogenate (10) | more than 500 (10% at 500 µM) |
| Isoepoxypteryxin (3) | 327.4 ± 3.4 | Chlorogenic acid (11) | inactive |
| Isopteryxin (4) | 475.9 ± 1.5 | Quercetin (12) | 35.5 ± 1.3 |
| β-Sitosterol-3-O-glucoside (5) | inactive | Kaempferol-3-O-glucoside (13) | 80.4 ± 5.1 |
| Hyuganin E (6) | 286.5 ± 2.1 | Kaempferol-3-O-rutinoside (14) | 50.4 ± 0.4 |
| 5-(Hydroxymethyl)-2-furaldehyde (7) | inactive | Adenosine (15) | inactive |
| Kaempferol (8) | more than 500 (30% at 250 µM) 2 |
1 Galantamine (positive control) IC50 = 1.4 ± 0.7 µM. 2,3 At higher concentrations; Non-linear relationship between higher concentration and enzyme activity was observed.