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. 2015 Mar 16;20(3):4813–4832. doi: 10.3390/molecules20034813

Table 1.

IC50 values of the isolated compounds in the AChEI assay 1.

Compound IC50 (µM) Compound IC50 (µM)
α-Glutinol (1) inactive Luteolin (9) more than 500 (30% at 250 µM) 3
β-Amyrin (2) inactive Methyl chlorogenate (10) more than 500 (10% at 500 µM)
Isoepoxypteryxin (3) 327.4 ± 3.4 Chlorogenic acid (11) inactive
Isopteryxin (4) 475.9 ± 1.5 Quercetin (12) 35.5 ± 1.3
β-Sitosterol-3-O-glucoside (5) inactive Kaempferol-3-O-glucoside (13) 80.4 ± 5.1
Hyuganin E (6) 286.5 ± 2.1 Kaempferol-3-O-rutinoside (14) 50.4 ± 0.4
5-(Hydroxymethyl)-2-furaldehyde (7) inactive Adenosine (15) inactive
Kaempferol (8) more than 500 (30% at 250 µM) 2

1 Galantamine (positive control) IC50 = 1.4 ± 0.7 µM. 2,3 At higher concentrations; Non-linear relationship between higher concentration and enzyme activity was observed.