Table 3.
The effects of H. teretifolium constituents on inhibition of Fe (II)-induced microsomal lipid peroxidation, tyrosinase and elastase activities.
| Sample | Inhibitory Activitis (IC50; μg/mL) * | ||
|---|---|---|---|
| Lipid Peroxidation | Tyrosinase | Elastase | |
| HT | 16.750 | 83.517 | 79.965 |
| 1 | >26.750 | >50 | >100 |
| 2 | >26.750 | >50 | >100 |
| 3 | 21.276 | >50 | >100 |
| 4 | >26.750 | >50 | >100 |
| 5 | >26.750 | >50 | >100 |
| 6 | 23.157 | >50 | >100 |
| 7 | 2.931 | 8.092 | 43.342 |
| 8 | 6.449 | 27.573 | >86.548 |
| 9 | 10.520 | 29.571 | >100 |
| 10 | 10.720 | 38.062 | >100 |
| EGCG | 0.929 | NA | NA |
| Kojic acid | NA | 3.425 | NA |
| Oleanolic acid | NA | NA | 9.806 |
* Data are given as IC50 with purified compounds screened at 26.750 μg/mL for inhibition of microsomal lipid peroxidation, while extract (HT) was screened at 100 μg/mL. Anti-tyrosinase activity for both extract and the purified compounds were screened at the effective concentration of 50 μg/mL, while 100 μg/mL was considered as optimum concentration for elastase assay.