Table 3.
Inhibitory effect of 1 and 2 on the S180 tumor growth in mice (mean ± S.D., n = 8 or 11).
Group | Dose (mg/kg) | Body Weight (g) | Tumor Weight (g) | Inhibition Rate (%) |
---|---|---|---|---|
Model group | — | 29.54 ± 3.61 | 2.45 ± 0.79 | — |
Taxol | 20 | 22.28 ± 2.02 * | 1.49 ± 0.46 * | 39.2 |
1 | 15 | 28.06 ± 3.09 | 2.10 ± 0.46 | 14.3 |
30 | 26.90 ± 2.95 | 1.79 ± 0.45 ** | 26.9 | |
2 | 15 | 28.63 ± 3.90 | 2.41 ± 0.72 | 1.6 |
30 | 27.22 ± 3.41 | 1.87 ± 0.41 ** | 23.7 |
Notes: * p < 0.01, ** p < 0.05, compared with model group; n = 8 for taxol group and n = 11 for other groups.