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. 2015 Feb 17;20(2):3406–3430. doi: 10.3390/molecules20023406

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© 2015 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Relative caspase-3 activity in (A) PC-3 and (B) DU 145 cells treated with MS17 for 12, 24, 48 and 72 h. Results are expressed as mean ± S.E. from three independent experiments and comparison between data sets was performed using ANOVA. * p < 0.05, ** p < 0.01 and *** p < 0.001 indicates statistically significant differences between the means of values obtained with treated vs. control. Caspase-3 inhibitor, Ac-DEVD-CHO was used as a control to determine the inhibitory activity of caspase-3.