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. 2015 Jun 17;20(6):11154–11172. doi: 10.3390/molecules200611154

Table 2.

Correlation between levels of biomarkers and clinical parameters of steroid naïve DMD ambulant patients. ** Correlation is significant at the 0.01 level (two-tailed). * Correlation is significant at the 0.05 level (two-tailed).

Biomarker Age (Years) NSAA 6 MW Barthel Brook L Vignos T10mw T10mr Gowers Stair Chair Shirt
MMP-9 Correlation coefficient 0.13 −0.34 0.16 0.05 0.29 0.39 0.2 0.650 ** 0.514 * 0.21 −0.12 0.39
p-Value 0.58 0.25 0.61 0.85 0.21 0.09 0.56 0.01 0.04 0.43 0.62 0.11
TIMP-1 Correlation coefficient −0.24 0.68 −0.23 0.07 −0.27 −0.07 0.09 0.05 0.09 0.39 −0.37 −0.09
p-Value 0.44 0.06 0.62 0.86 0.38 0.82 0.82 0.89 0.81 0.29 0.32 0.81
GDF-8 Correlation coefficient 0.02 −0.13 -0.3 −0.33 −0.22 −0.16 −0.27 −0.36 −0.13 −0.09 0.29 −0.07
p-Value 0.95 0.75 0.4 0.32 0.47 0.61 0.42 0.25 0.7 0.8 0.39 0.84
MMP-2 Correlation coefficient −0.1 0.41 0.13 0.3 −0.3 −0.37 0.29 0.03 −0.25 −0.17 −0.586 * −0.41
p-Value 0.68 0.16 0.67 0.37 0.22 0.13 0.41 0.9 0.39 0.55 0.02 0.11
FSTN Correlation coefficient −0.22 −0.14 −0.02 0.02 0.30 0.03 0.19 0.17 0.00 0.1 −0.07 0.16
p-Value 0.38 0.64 0.94 0.94 0.21 0.91 0.59 0.51 0.99 0.73 0.79 0.56