Table 4.

Effect of Nigella ethanolic extracts and furosemide on urine output and uric acid in 24 h of urine collection. Drugs were given orally (n = 6).

Group	Dose	Diurese (mL∙kg−1/24 h)	Diuretic Index	Uric Acid (mg∙kg−1/24 h)
Control		9.54 ± 0.93	1	2.7 ± 0.26
Furosemide	30 mg∙kg−1	40.58 ± 6.39 A	4.25	2.55 ± 0.43
N. sativa	100 mg∙kg−1	14.59 ± 2.85 a	1.53	2.32 ± 0.45
N. damascena	100 mg∙kg−1	9.61 ± 1.47	1.01	2.35 ± 0.36

Notes: Each value is the mean ± SD of three independent measurements; Diuretic index (DI) = volume treated group/volume control group; Results marked with capital letters showed highly significant statistical difference (p < 0.001) compared to control; results marked with uncapitalized showed significant statistical difference (0.001 < p < 0.05).