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. 2015 Jun 19;20(6):11317–11344. doi: 10.3390/molecules200611317

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© 2015 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Comparative profiling of wild type (wt) muscles vs. dystrophic diaphragm (DIA), soleus (SOL), extensor digitorum longus (EDL), flexor digitorum brevis (FDB), and interosseus (INT) muscles from the mdx animal model of Duchenne muscular dystrophy. (A) Workflow of the comparative proteomic analysis of normal vs. dystrophic skeletal muscles; (B) Silver-stained gel of the mdx and wt preparations from DIA (lanes 1 and 2), SOL (lanes 3 and 4), EDL (lanes 5 and 6), FDB (lanes 7 and 8), and INT (lanes 9 and 10) muscles; (C) Comparative immunoblot analysis of β-dystroglycan showing antibody labelling of this dystrophin-associated glycoprotein of 43 kDa in normal vs. dystrophic muscles.