Table 2.

Cytotoxicity of the isolated compounds from A. mellea against several cancer cell lines ^a.

Compound	IC50 (μM)
	MCF-7	H460	HT-29	CEM
1	56.5 ± 4.2	5.5 ± 0.6	7.1 ± 0.8	5.4 ± 0.3
2	1.5 ± 0.1	80.0 ± 8.9	54.2 ± 4.7	10.3 ± 2.3
3	3.7 ± 0.3	53.8 ± 6.2	18.7 ± 3.2	3.4 ± 0.2
4	4.8 ± 0.5	4.5 ± 0.4	56.7 ± 4.5	28.8 ± 1.2
5	>100	>100	32.1 ± 3.6	5.5 ± 0.6
6	4.8 ± 0.4	5.5 ± 0.4	4.6 ± 0.3	5.8 ± 0.6
7	1.7 ± 0.2	4.5 ± 0.3	42.1 ± 5.1	5.1 ± 0.4
8	4.4 ± 0.8	5.7 ± 0.5	34.7 ± 4.6	44.6 ± 4.4
9	8.3 ± 2.2	5.1 ± 0.2	58.4 ± 4.9	41.2 ± 3.4
10	>100	>100	85.6 ± 9.1	49.6 ± 5.2
11	>100	>100	>100	>100
Dox	0.27 ± 0.02	0.01 ± 0.005	0.12 ± 0.01	0.09 ± 0.01

^a MCF-7, human breast cancer; H460, human lung cancer; HT-29, human colon cancer; CEM, human leukaemia. Dox: Doxorubicin as a positive control.