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. 2015 Jun 18;20(6):11272–11296. doi: 10.3390/molecules200611272

Table 1.

Antibacterial activity of structurally related compounds and parent terpenes against Gram-positive and Gramnegative reference strains.

Compound Minimum Inhibitory Concentrations MIC (µg/mL)
Gram-Positive Bacteria Gram-Negative Bacteria
Staphylococcus aureus ATCC 43300 Enterococcus faecalis ATCC 51299 Enterococcus faecium ATCC 35667 Escherichia coli ATCC 25922 Klebsiella pneumoniae ATCC 700603 Acinetobacter baumannii ATCC 19606
Geranyl acetone (1) 48 36 28 26 18 18
6 26 18 16 14 14 12
7 26 16 18 16 16 14
8 38 26 28 18 18 22
9 28 18 14 28 18 16
10 46 26 18 32 18 16
11 26 22 18 28 28 14
Nerolidol (2) 48 38 32 46 16 26
12 48 46 42 40 28 26
13 46 42 38 40 20 22
14 48 38 36 38 18 28
15 46 48 38 28 16 16
16 48 38 36 32 24 22
17 48 38 38 46 18 16
Farnesal (3) 24 22 36 46 44 36
18 18 22 28 52 46 46
19 28 34 38 44 36 42
20 22 20 32 48 38 38
21 32 38 42 54 48 52
22 26 24 46 44 36 36
23 28 26 36 46 34 36
Farnesol (4) 26 18 16 28 16 18
24 22 18 32 52 44 40
25 28 32 34 50 48 44
26 32 30 36 48 42 38
27 28 26 18 36 18 34
28 26 18 16 28 16 18
29 28 22 18 38 36 32
Farnesyl acetate (5) 28 20 20 28 22 22
30 30 24 18 30 24 24
31 24 20 20 26 22 18
32 28 22 20 28 18 22
33 26 18 16 26 18 22
34 32 20 18 18 20 18
35 34 16 14 16 18 12
Ciprofloxacin 8 2 8 4 2 4
Gentamicin 16 >64 * 32 4 32 32

* The maximum examined concentration was 64 µg/mL.