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. 2015 Apr 27;20(5):7620–7636. doi: 10.3390/molecules20057620

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© 2015 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Predicted binding mode of compound 5k with the SET-domain of EZH2. Compound 5k is shown in green. EZH2 is represented by ribbons with the interacting residues represented as sticks. Hydrogen-bonding is drawn as dashed blue.