. 2015 Apr 27;20(5):7620–7636. doi: 10.3390/molecules20057620

Table 4.

Inhibition activity of 5k against EZH2 and several other selected histone methyltransferases.

Targets	EZH2	SMYD3	G9a	SUV39H1	SETDB1	PRMT1	SETD8
IC₅₀ ^a (μM)	1.20 ± 0.11	35.4 ± 1.97	82.6 ± 2.23	21.2 ± 0.28	27.0 ± 1.36	28.8 ± 1.25	40.0 ± 2.71

^a Values are means of at least three measurements.