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. 2015 Jan 8;20(1):900–912. doi: 10.3390/molecules20010900

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© 2015 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Effects of flavonols on TRAIL-R1 expression in RAW264.7 cells (a); Cells were incubated with LPS (200 ng/mL) (b); with LPS and galangin (c); with LPS and kaempferol (d), with LPS and kaempferide (e) and with LPS and quercetin (f) at concentration of 20 μM. The surface expression of TRAIL-R1 death receptor was measured by flow cytometric analysis. The values represent mean ± SD of three independent experiments, performed in duplicate n = 6. *** p < 0.001 compared to isotype control. ^### p < 0.001 compared to LPS-stimulated cells.

Effects of flavonols on TRAIL-R1 expression in RAW264.7 cells (a); Cells were incubated with LPS (200 ng/mL) (b); with LPS and galangin (c); with LPS and kaempferol (d), with LPS and kaempferide (e) and with LPS and quercetin (f) at concentration of 20 μM. The surface expression of TRAIL-R1 death receptor was measured by flow cytometric analysis. The values represent mean ± SD of three independent experiments, performed in duplicate n = 6. *** p < 0.001 compared to isotype control. ^### p < 0.001 compared to LPS-stimulated cells.