Table 2.
Frequencies of micronucleated polychromatic erythrocytes (MNPECs) in bone marrow of mice after various treatments.
| Group | No. of Animal | Polysaccharide Dose (g/kg·BW) | Se Dose (μg/kg·BW) | No. of Analyzed Cells | MNPEC | Reduction (%) | |
|---|---|---|---|---|---|---|---|
| No. | % | ||||||
| 0.9% NaCl | 10 | 0 | 0 | 10,000 | 31 ± 3 | 0.31 ± 0.03 | |
| CP | 10 | 0 | 0 | 10,000 | 624 ± 17 | 6.24 ± 0.17 a | |
| Se-PFPs (a) + NaCl | 10 | 1.35 | 5 | 10,000 | 25 ± 5 | 0.25 ± 0.05 | |
| Se-PFPs (b) + NaCl | 10 | 2.7 | 10 | 10,000 | 26 ± 4 | 0.26 ± 0.04 | |
| Se-PFPs (c) + NaCl | 10 | 5.4 | 20 | 10,000 | 29 ± 4 | 0.29 ± 0.04 | |
| PFPs + NaCl | 10 | 2.7 | 0.108 | 10,000 | 28 ± 5 | 0.28 ± 0.05 | |
| Se + NaCl | 10 | 0 | 10 | 10,000 | 27 ± 4 | 0.27 ± 0.04 | |
| PFPs + Se + NaCl | 10 | 2.7 | 10 | 10,000 | 25 ± 4 | 0.25 ± 0.04 | |
| Se-PFPs (a) + CP | 10 | 1.35 | 5 | 10,000 | 281 ± 9 | 2.81 ± 0.09 b | 57.8 |
| Se-PFPs (b) +CP | 10 | 2.7 | 10 | 10,000 | 186 ± 7 | 1.86 ± 0.07 b | 73.9 |
| Se-PFPs (c) + CP | 10 | 5.4 | 20 | 10,000 | 112 ± 10 | 1.12 ± 0.10 b,d | 86.3 |
| PFPs + CP | 10 | 2.7 | 0.108 | 10,000 | 377 ± 10 | 3.77 ± 0.10 b | 41.7 |
| Se + CP | 10 | 0 | 10 | 10,000 | 362 ± 9 | 3.62 ± 0.09 b,c | 44.2 |
| PFPs + Se + CP | 10 | 2.7 | 10 | 10,000 | 253 ± 9 | 2.53 ± 0.09 b,c | 62.6 |
a p < 0.05, compared with 0.9% NaCl; b p < 0.05, compared with CP; c p < 0.05, compared with Se-PFPs (b) + CP; d p < 0.05, compared with Se-PFPs (a) + CP. CP, cyclophosphamide; PFPs, polysaccharides from P. fortuneana; Se, selenite; Se-PFPs, polysaccharide from Se-enriched P. fortuneana; BW, body weight.