Table 4.

Chemical structures and yields obtained for the sequential MCR-synthesis of 8a, 8c and 8h–m via Cu catalysed intramolecular cyclization.

-R1	-R2	Compound	Time a (h)	Yield b (%)
	H	8a	1	80
	H	8c	2	96
	H	8h	1	89
	H	8i	0.5	88
	H	8j	0.5	87
	H	8k	0.5	86
	H	8l	0.5	90
	H	8m	12	77

^a Time of the conversion of 13 into the corresponding thioureas (step 1); ^b Isolated yield.