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. 2016 Mar 10;21(3):325. doi: 10.3390/molecules21030325

Figure 2.

Figure 2

SC79 administration after SAH improves the disrupted iron homeostasis. (A) Western blotting for the protein levels of TfR, ferritin, Fpn1, IRP1, and IRP2 of the rat temporal cortex. Left panel: a representative protein levels of TfR, ferritin, Fpn1, IRP1, and IRP2. Right panel: quantitative data of the protein levels. Tubulin was detected as a loading control; (B) Prussian blue iron staining; and (C) iron content determined by ferrozine assays. Data are expressed as mean ± SD (n = 8 in each group). * p < 0.05, ** p < 0.01, *** p < 0.001 vs. the sham group, # p < 0.05, ## p < 0.01, ### p < 0.001 vs. the SAH group. Definition of sham, SAH, SAH + vehicle, and SAH + SC79 groups is the same as in Figure 1. Fpn1, ferroportin 1; TfR, transferrin receptor, IRP1/2, iron regulatory protein 1/2.