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. 2016 Dec 21;21(12):1756. doi: 10.3390/molecules21121756

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© 2016 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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The in vivo effect of SPN and Conbercept on retinopathy of rats in ADPase-stained retinal sections (40×). Central retinal region of rat pups fostered under normoxia conditions (a1); OIR rats intraperitoneally administered with NS (b1), 1.0 mg/kg Conbercept (c1), 5.0 mg/kg SPN (d1) or 10.0 mg/kg SPN (e1). Peripheral retinal region of control, rat pups fostered under normoxia conditions (a2); OIR rats intraperitoneally administered with NS (b2), 1.0 mg/kg Conbercept (c2), 5.0 mg/kg SPN (d2) or 10.0 mg/kg SPN (e2). Ten rats were used for each group (n = 10).

The in vivo effect of SPN and Conbercept on retinopathy of rats in ADPase-stained retinal sections (40×). Central retinal region of rat pups fostered under normoxia conditions (a1); OIR rats intraperitoneally administered with NS (b1), 1.0 mg/kg Conbercept (c1), 5.0 mg/kg SPN (d1) or 10.0 mg/kg SPN (e1). Peripheral retinal region of control, rat pups fostered under normoxia conditions (a2); OIR rats intraperitoneally administered with NS (b2), 1.0 mg/kg Conbercept (c2), 5.0 mg/kg SPN (d2) or 10.0 mg/kg SPN (e2). Ten rats were used for each group (n = 10).