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. 2016 Nov 14;21(11):1531. doi: 10.3390/molecules21111531

Table 3.

Non-compartmental pharmacokinetic parameters of rutin following oral administration in Balb/c mice (dose 10 mg).

Pharmakokinetic Parameter Suspension NADES
tmax (min) 15 60
Cmax (ng/mL) 28.6 58.3
t1/2 λz (min) 106 86
AUClast (ng min/mL) 2225 4862
AUC (ng min/mL) 2888 5806
AUC (%Extrapolated) 23 16
MRT (min) 158 131