The anabolic biosynthetic and catabolic pathways of polyamines metabolome, where 1,3-diaminopropane, putrescine, cadaverine, spermidine, spermine, agmatine s, N-acetylputrescine, N-acetylspermine, N-acetylspermidine are polyamines, l-ornithine, lysine, l-arginine, S-adenosyl-l-methionine are amino acid which can form polyamines, and γ-aminobutyric acid are catabolic of polyamines. The notations here are ornithine decarboxylase (ODC), diamine oxidase (DAO), S-adenosylmethionine decarboxylase (SAMDC), Spermidine and spermine acetyl transferase (SSAT) and flavin adenine dinucleotide-polyamine oxidase (FAD-PAO).