Treatment (mg/kg; i.p.) | Latency (s) | |||
---|---|---|---|---|
Clonus | Tonus | Death | ||
Vehicle | Saline | 164 (152–177) | 681 (618–750) | 706 (586–851) |
OJe | 20 | 174 (158–192) | 712 (584–868) | 776 (645–934) |
40 | 194 (176–214) | 852 (695–1044) * | 918 (746–1130) * | |
80 | 211 (192–230) | 868 (684–1102) * | 909 (684–1208) * | |
HES | 40 | 176 (156–198) | 734 (592–910) | 804 (672–962) |
80 | 184 (160–211.6) | 845 (683–1110) * | 878 (724–1064.8) * | |
NRTN | 40 | 168 (150–201) | 756 (564–900) | 801 (644–966) |
80 | 179 (155–206.7) | 784 (598–1027.8) | 834 (696–999.4) |