Treatment (mg/kg; 5 Days; os) | Latency (s) | |||
---|---|---|---|---|
Clonus | Tonus | Death | ||
Vehicle | Saline | 158 (140–178) | 664 (598–737) | 712 (604–839) |
OJe | 20 | 160 (140–180) | 670 (494–697) | 788 (602–946) |
40 | 224 (198–253) | 928 (715–1204) * | 998 (776–1284) * | |
HES | 40 | 168 (150–201) | 756 (564–900) | 801 (644–966) |
80 | 218 (200–248) | 899 (709–1198) * | 995 (788–1226) * | |
NRTN | 40 | 155 (146–198) | 744 (526–897) | 798 (625–978) |
80 | 196 (150–201) | 767 (602–916) | 802 (627–974) |