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. 2016 Dec 13;21(12):1716. doi: 10.3390/molecules21121716

Table 1.

Data for amides derived from cinnamic acid and benzoic acid.

graphic file with name molecules-21-01716-i001.jpg graphic file with name molecules-21-01716-i002.jpg
Compound R1 R2 R3 R4 R5 Molecular Formula Reaction Time (h) Yield (%)
1 - - - - Cl C16H14ClNO 3 75
2 - OH OH - Cl C16H14ClNO3 7 70
3 - OMe OH - Cl C17H16ClNO3 4 81
4 - - OMe - Cl C17H16ClNO2 2 91
5 OH - - - Cl C16H14ClNO2 5 79
6 - OH - - Cl C16H14ClNO2 4 76
7 - - OH - Cl C16H14ClNO2 3 63
8 - - Cl - Cl C16H13Cl2NO 2 71
9 - OMe OH OMe Cl C18H18ClNO4 6 60
10 NO2 - - - Cl C16H13ClN2O3 2 79
11 - OMe OMe OMe Cl C19H20ClNO4 3 86
12 - - - - Cl C14H12ClNO 3 65
13 - - C6H5 Cl C20H16ClNO 6 56
14 - OH OH OH Cl C14H12ClNO4 3 21
15 - OMe OH - Cl C15H14ClNO3 6 44
16 - OMe OH OMe Cl C16H16ClNO4 3 50
17 - - OH - Cl C14H12ClNO2 3 73
18 - C(CH3)3 OH C(CH3)3 Cl C22H28ClNO2 3 54
19 - OH - OMe Cl C15H14ClNO3 6 60
20 - Me - NO2 Cl C15H13ClN2O3 4 41
21 - OMe OH - F C15H14FNO3 2 27
22 - OMe OH - Br C15H14BrNO3 2 63