Table 3.

Evaluation of MIC (µg/mL) of the amides derived from cinnamic acid and benzoic acid in the microdilution broth assay.

MIC b (µg·mL−1)/Yeast
Compound	C. albicans ATCC-76645	C. albicans LM-106	C. albicans LM-23	C. tropicalis ATCC-13803	C. tropicalis LM-36	C. krusei LM-13	C. krusei LM-656
1	1024	1024	1024	512	512	+	1024
2	256	256	256	512	1024	512	512
3	256	256	256	512	512	512	512
4	+	+	+	+	+	+	+
5	256	256	256	512	512	1024	1024
6	256	256	256	512	512	1024	1024
7	1024	1024	512	+	+	+	1024
8	+	+	+	+	+	+	+
9	+	+	+	+	+	+	+
10	256	256	256	256	256	512	512
11	+	+	+	+	+	+	+
12	+	+	+	+	+	+	+
13	+	+	+	+	+	+	+
14	256	256	512	512	512	256	256
15	512	256	256	256	256	256	256
16	+	+	+	+	+	+	+
17	+	+	+	+	1024	+	256
18	+	+	+	+	+	+	+
19	+	+	+	+	+	+	+
20	+	+	+	+	+	+	+
21	512	512	512	+	+	1024	1024
22	+	+	+	+	+	+	+
23	+	+	+	+	+	+	+
24	+	+	+	+	+	+	+
25	+	+	+	+	+	+	+
26	+	+	+	+	+	+	+
27	+	+	+	+	+	+	+
28	+	+	+	+	+	+	+
29	+	+	+	+	+	+	+
30	+	+	+	+	+	+	+
31	+	+	+	+	+	+	+
32	+	+	+	+	+	+	+
Nystatin	3.125	3.125	3.125	3.125	3.125	3.125	3.125

+ Growth of the microorganism ^b MIC defined as the lowest concentration that produced 50% reduction in fungal cell growth after 24 h of incubation.