Table 2.
Cytotoxic activities of compounds 1–8 isolated from C. kiangsiense (IC50 in μM).
| Compounds | HL-60 | SMMC-7721 | A-549 | MCF-7 |
|---|---|---|---|---|
| 1 | 12.5 ± 1.2 | 13.6 ± 0.8 | 7.4 ± 1.1 | 27.7 ± 2.2 |
| 2 | 18.6 ± 1.8 | 15.9 ±1.6 | 10.2 ± 1.2 | 15.4 ± 2.7 |
| 3 | 23.5 ± 2.0 | 33.0 ± 2.4 | 10.4 ± 1.3 | 19.2 ± 1.8 |
| 4 | 9.9 ± 0.9 | 6.7 ± 1.0 | 8.7 ± 0.8 | 10.0 ± 0.8 |
| 5 | 15.5 ± 1.9 | 15.7 ± 1.6 | 11.8 ± 2.4 | 22.4 ± 2.9 |
| 6 | 4.8 ± 0.5 | 3.8 ± 0.9 | 2.7 ± 0.7 | 5.0 ± 1.0 |
| 7 | 15.7 ± 1.8 | 5.8 ± 0.8 | 7.9 ± 0.7 | 19.2 ± 1.4 |
| 8 | 1.8 ± 0.3 | 4.9 ± 0.7 | 2.5 ± 0.7 | 3.1 ± 0.5 |
| Cisplatin | 4.2 ± 0.5 | 5.9 ± 0.9 | 9.8 ± 1.1 | 11.3 ± 1.0 |
Results are expressed as means of IC50 values (the concentration that reduced cell growth by 50%) in μM, and data were obtained from triplicate experiments.