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. 2016 May 11;21(5):615. doi: 10.3390/molecules21050615

Scheme 14.

Scheme 14

Synthetic scheme for generating indolylthiobarbituric acid derivatives 68. Reagents and Conditions: (i) NaOMe, MeOH, 60 °C, 6 h, yields not reported; (ii) NaH, DMF, RT, overnight, 83%; (iii) 6 M HCl, EtOH, RT, 2–3 h, yields not reported.