Table 8.

K_I values (μM) for compounds 60, 62, 64, 69–71 and AZA of some human (h) and bovine (b) α-carbonic anhydrase isoforms (by an esterase assay) [67].

No.	KI (nM) a
	hCA I	hCA II	bCA III	hCA IV	hCA VI
Apigenin (60)	0.97	0.113	2.21	1.12	1.49
Quercetin (62)	2.68 b	2.54 b	3.73	7.89 b	6.17 b
Catechin (64)	1.73	0.83	4.77	3.76	7.82
Rutin (69)	2.42 b	1.84 b	9.71	4.09 b	4.91 b
Epicatechin (70)	2.32	1.24	8.93	3.98	4.36
Silymarin (71)	1.49 c	2.51 c	5.68	8.96 c	9.70 c
AZA	36.2	0.37	263	0.578	0.34

^a From three different assays, errors ± 5%–10% of the reported value. ^b Values from Ref. [68]; ^c Values form Ref. [66].