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. 2016 Sep 27;21(10):1292. doi: 10.3390/molecules21101292

Table 4.

Correlation coefficient (r) between phenolic compositions of mature, immature, and steamed immature wheat bran and antioxidant capacity or cellular antioxidant activity or cell growth inhibition or apoptotic cell death.

Phenolic Compositions ORAC CAA Cell Growth Inhibition Apoptotic Cell Death
Caco-2 HT-29 HeLa
Ferulic acid Free −0.170 –0.477 −0.352 −0.191 −0.689 * −0.278
Bound 0.815 ** 0.988 *** 0.939 *** 0.863 *** 0.975 *** 0.882 ***
Sinapic acid Free 0.645 0.914 *** 0.829 ** 0.786 * 0.927 *** 0.828 ***
Bound −0.685 * −0.530 −0.615 −0.468 −0.356 −0.305
Vanillic acid Free 0.397 0.054 0.201 0.188 −0.210 0.103
Bound −0.428 −0.689 * −0.581 −0.402 −0.833 *** −0.471
p-Coumaric acid Free 0.823 ** 0.961 *** 0.933 *** 0.748 * 0.933 *** 0.795 ***
Bound 0.779 * 0.950 *** 0.954 *** 0.918 *** 0.912 *** 0.966 ***
Syringic acid Free 0.460 0.211 0.297 0.390 −0.085 0.269
Bound −0.716 * −0.871 ** −0.768 * −0.637 −0.906 *** −0.619
Syringaldehyde Free 0.713 * 0.940 *** 0.880 ** 0.749 * 0.989 *** 0.812 ***
Bound 0.781 * 0.961 *** 0.960 *** 0.856 ** 0.956 *** 0.890 ***
Caffeic acid Free −0.301 −0.488 −0.481 −0.235 −0.675 * −0.366
Bound 0.405 0.562 0.446 0.274 0.676 * 0.261

Caco-2, HT-29, and HeLa cells represent relative inhibition % of cell growth for Caco-2, HT-29, and HeLa cells, which were treated with 20 mg/mL of wheat bran extracts. Values in bold with *, ** and *** are different from 0 with significance level at p < 0.05, p < 0.01 and p < 0.001, respectively.