Table 4.
Phenolic Compositions | ORAC | CAA | Cell Growth Inhibition | Apoptotic Cell Death | |||
---|---|---|---|---|---|---|---|
Caco-2 | HT-29 | HeLa | |||||
Ferulic acid | Free | −0.170 | –0.477 | −0.352 | −0.191 | −0.689 * | −0.278 |
Bound | 0.815 ** | 0.988 *** | 0.939 *** | 0.863 *** | 0.975 *** | 0.882 *** | |
Sinapic acid | Free | 0.645 | 0.914 *** | 0.829 ** | 0.786 * | 0.927 *** | 0.828 *** |
Bound | −0.685 * | −0.530 | −0.615 | −0.468 | −0.356 | −0.305 | |
Vanillic acid | Free | 0.397 | 0.054 | 0.201 | 0.188 | −0.210 | 0.103 |
Bound | −0.428 | −0.689 * | −0.581 | −0.402 | −0.833 *** | −0.471 | |
p-Coumaric acid | Free | 0.823 ** | 0.961 *** | 0.933 *** | 0.748 * | 0.933 *** | 0.795 *** |
Bound | 0.779 * | 0.950 *** | 0.954 *** | 0.918 *** | 0.912 *** | 0.966 *** | |
Syringic acid | Free | 0.460 | 0.211 | 0.297 | 0.390 | −0.085 | 0.269 |
Bound | −0.716 * | −0.871 ** | −0.768 * | −0.637 | −0.906 *** | −0.619 | |
Syringaldehyde | Free | 0.713 * | 0.940 *** | 0.880 ** | 0.749 * | 0.989 *** | 0.812 *** |
Bound | 0.781 * | 0.961 *** | 0.960 *** | 0.856 ** | 0.956 *** | 0.890 *** | |
Caffeic acid | Free | −0.301 | −0.488 | −0.481 | −0.235 | −0.675 * | −0.366 |
Bound | 0.405 | 0.562 | 0.446 | 0.274 | 0.676 * | 0.261 |
Caco-2, HT-29, and HeLa cells represent relative inhibition % of cell growth for Caco-2, HT-29, and HeLa cells, which were treated with 20 mg/mL of wheat bran extracts. Values in bold with *, ** and *** are different from 0 with significance level at p < 0.05, p < 0.01 and p < 0.001, respectively.