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. 2016 Dec 6;21(12):1680. doi: 10.3390/molecules21121680

Table 4.

Enzyme–Hoveyda–Grubbs second-generation catalyst sol–gel conjugate in metathesis reaction of 1.1

Entry Sol–Gel Conjugate Time (h) Conversion 2 (%)
1 - 2 2 65
2 Hoveyda–Grubbs 2 <2
3 CAL-B 2 0
4 CAL-B–Hoveyda–Grubbs 2 60 (36) 3

1 Reaction conditions: 1 (8 µL, 0.033 mmoles), THF (1 mL), catalyst (20 mg) and 25 °C; 2 the reaction performed with the soluble catalyst (0.3 mg); 3 conversion after third cycle.