Table 1.

Activity Classes for cyclooxygenase-2 (COX2) estrogen receptor (ER) and benzodiazepine receptor (BZR) Datasets.

Datasets	Number of Compounds				Pairwise Similarity (Mean)
	Active		Inactive		Active	Inactive
	Training	Validation	Training	Validation
Cyclooxygenase-2 inhibitors	211	92	116	48	0.687	0.690
Benzodiazepine receptor	214	92	70	29	0.536	0.538
Estrogen receptor	86	55	190	62	0.468	0.456