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Drug association efficiency and microparticle loading capacity determined for LBG microparticles (mean ± SD, n = 3).
| Formulation | LBG/Drug (w/w) | Association Efficiency (%) | Loading Capacity (%) |
|---|---|---|---|
| LBG:INH | 10:1 | 88.8 ± 1.5 | 8.8 ± 0.1 |
| LBG:RFB | 10:0.2 | 92.4 ± 6.0 | 1.8 ± 0.1 |
| 10:0.5 | 86.3 ± 3.0 | 4.1 ± 0.1 | |
| 10:1 | 102.8 ± 3.8 | 10.3 ± 0.4 |
INH: isoniazid, LBG: locust bean gum, RFB: rifabutin.
