Effect of DMFP in formalin-induced paw-licking test (early phase, panel (A); and late phase, panel (B) in mice. Each column represents the mean ± S.E.M. (n = 6). The mice were pretreated with vehicle C, 10 mL/kg, i.p.), DMFP (0.1, 0.5, 1.0 and 5.0 mg/kg, i.p.), acetylsalicylic acid (ASA, 100 mg/kg, i.p.) or morphine (MOR, 5 mg/kg, i.p.). The asterisks denote the significance levels * p < 0.5, ** p < 0.01, *** p < 0.001, when compared with control vehicle group. Statistical significance was determined by one-way ANOVA followed by Dunnett’s post-hoc test. Values in parentheses are percentage of inhibition.