. 2016 Mar 7;21(3):318. doi: 10.3390/molecules21030318

Table 2.

Continuous-flow deuteration of 6 ^a.

graphic file with name molecules-21-00318-i002.jpg

Entry	Catalyst	p (bar)	T (°C)	Total Conversion ^b (%)	Product Ratio ^b (%)
Entry	Catalyst	p (bar)	T (°C)	Total Conversion ^b (%)	6a ^c	6b	6c
1	Lindlar catalyst	10	25	23	90	10	0
2	Lindlar catalyst	20	25	40	86	14	0
3	Lindlar catalyst	40	25	57	81	19	0
4	Lindlar catalyst	80	25	63	80	20	0

^a: Conditions: c = 1 mg·mL^‒1 in ethyl acetate, 1 mL·min^–1 flow rate; ^b: Determined by GC-MS analysis of the crude material; ^c: During the reactions, the (Z) deuterated chalcone isomer is formed, but readily isomerizes to the more stable (E) form.